Oncolysis by a new strain of Clostridium.

Oncolysis by Clostridia. I. Activity of Clostridium Butyricum (m-55) and Other Nonpathogenic Clostridia against the Ehrlich Carcinoma.

Intravenous injections of suspensions of spores of Cl. butyricum (Strain M-55) pro duced a more or less extensive lysis of tumor tissue. A number of other strains of nonpathogenic Clostridia did not show substantially improved results. In general, strains which were able to ferment carbohydrate performed equally well, whereas pri marily proteolytic strains gave inferior results. Combination of ...

Characteristics of a bacteriocin -like substance produced by Clostridium haemolyticum strain IRP - 135

Some properties of Beta Toxin produced by Clostridium haemolyticum strain IRP 13

Molecular cloning of Clostridium septicum vaccine strain alpha toxin gene in E. coli

Clostridium septicum a Gram positive anaerobic bacterium produces several toxins including alpha, beta, gamma and delta. C. septicum alpha toxin is lethal and is responsible for a serious disease known as gas gangrene. The aim of the present study was to molecular cloning and sequencing of C. septicum vaccine strain alpha toxin gene. Genomic DNA was extracted using standard phenol and chlorofor...

Cloning of Clostridium perfringens iota toxin gene in Escherichia coli

Iota toxin is produced by Clostridium perfringens type E. This toxin causes antibiotic-associated enterotoxemia in lambs and calves. Iota toxin is a binary toxin that has two components including Ia (the enzyme component) and Ib (the binding component). Ib binds to the surface receptor of target cells and translocate Ia into the cytosol of cells. The aim of this study was to clone toxigenic epi...